2020-2022
Moormann J, Heinemann B, Hildebrandt TM (2022) News about amino acid metabolism in plant-microbe interactions. Trends in biochemical sciences 47 (10):839–850. https://doi.org/10.1016/j.tibs.2022.07.001.
Brito DS, Quinhones CGS, Neri-Silva R, Heinemann B, Schertl P, Cavalcanti JHF, Eubel H, Hildebrandt T, Nunes-Nesi A, Braun H-P, Araújo WL (2022) The role of the electron-transfer flavoprotein: ubiquinone oxidoreductase following carbohydrate starvation in Arabidopsis cell cultures. Plant cell reports 41 (2):431–446. https://doi.org/10.1007/s00299-021-02822-1.
Heinemann B, Künzler P, Eubel H, Braun H-P, Hildebrandt TM (2021) Estimating the number of protein molecules in a plant cell: protein and amino acid homeostasis during drought. Plant physiology 185 (2):385–404. https://doi.org/10.1093/plphys/kiaa050.
Moseler A, Kruse I, Maclean AE, Pedroletti L, Franceschetti M, Wagner S, Wehler R, Fischer-Schrader K, Poschet G, Wirtz M, Dörmann P, Hildebrandt TM, Hell R, Schwarzländer M, Balk J, Meyer AJ (2021) The function of glutaredoxin GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria. Plant physiology 186 (3):1507–1525. https://doi.org/10.1093/plphys/kiab172.
Heinemann B, Hildebrandt TM (2021) The role of amino acid metabolism in signaling and metabolic adaptation to stress-induced energy deficiency in plants. Journal of experimental botany 72 (13):4634–4645. https://doi.org/10.1093/jxb/erab182.
Fuchs P, Rugen N, Carrie C, Elsässer M, Finkemeier I, Giese J, Hildebrandt TM, Kühn K, Maurino VG, Ruberti C, Schallenberg-Rüdinger M, Steinbeck J, Braun H-P, Eubel H, Meyer EH, Müller-Schüssele SJ, Schwarzländer M (2020) Single organelle function and organization as estimated from Arabidopsis mitochondrial proteomics. The Plant journal : for cell and molecular biology 101 (2):420–441. https://doi.org/10.1111/tpj.14534.
2017-2019
Farhat N, Hichri S, Hildebrandt TM, Debez A, Braun H-P (2019) Composition and Stability of the Oxidative Phosphorylation System in the Halophile Plant Cakile maritima. Frontiers in plant science (10):1010. https://doi.org/10.3389/fpls.2019.01010.
Batista-Silva W, Heinemann B, Rugen N, Nunes-Nesi A, Araújo WL, Braun H-P, Hildebrandt TM (2019) The role of amino acid metabolism during abiotic stress release. Plant, cell & environment 42 (5):1630–1644. https://doi.org/10.1111/pce.13518.
Brandt S, Fachinger S, Tohge T, Fernie AR, Braun H-P, Hildebrandt TM (2018) Extended darkness induces internal turnover of glucosinolates in Arabidopsis thaliana leaves. PloS one 13 (8):e0202153. https://doi.org/10.1371/journal.pone.0202153.
Lorenz C, Brandt S, Borisjuk L, Rolletschek H, Heinzel N, Tohge T, Fernie AR, Braun H-P, Hildebrandt TM (2018) The Role of Persulfide Metabolism During Arabidopsis Seed Development Under Light and Dark Conditions. Frontiers in plant science (9):1381. https://doi.org/10.3389/fpls.2018.01381.
Hildebrandt TM (2018) Synthesis versus degradation: directions of amino acid metabolism during Arabidopsis abiotic stress response. Plant molecular biology 98 (2):121–135. https://doi.org/10.1007/s11103-018-0767-0.
Belghith I, Senkler J, Hildebrandt T, Abdelly C, Braun H-P, Debez A (2018) Comparative analysis of salt-induced changes in the root proteome of two accessions of the halophyte Cakile maritima. Plant Physiology and Biochemistry 130 (1):20–29. https://doi.org/10.1016/j.plaphy.2018.06.029.
Cavalcanti JHF, Quinhones CGS, Schertl P, Brito DS, Eubel H, Hildebrandt T, Nunes-Nesi A, Braun H-P, Araújo WL (2017) Differential impact of amino acids on OXPHOS system activity following carbohydrate starvation in Arabidopsis cell suspensions. Physiologia plantarum 161 (4):451–467. https://doi.org/10.1111/ppl.12612.
Luna-Sánchez M, Hidalgo-Gutiérrez A, Hildebrandt TM, Chaves-Serrano J, Barriocanal-Casado E, Santos-Fandila Á, Romero M, Sayed RK, Duarte J, Prokisch H, Schuelke M, Distelmaier F, Escames G, Acuña-Castroviejo D, López LC (2017) CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome. EMBO molecular medicine 9 (1):78–95. https://doi.org/10.15252/emmm.201606345.
Senkler J, Senkler M, Eubel H, Hildebrandt T, Lengwenus C, Schertl P, Schwarzländer M, Wagner S, Wittig I, Braun H-P (2017) The mitochondrial complexome of Arabidopsis thaliana. The Plant journal : for cell and molecular biology 89 (6):1079–1092. https://doi.org/10.1111/tpj.13448.
2014-2016
Höfler S, Lorenz C, Busch T, Brinkkötter M, Tohge T, Fernie AR, Braun H-P, Hildebrandt TM (2016) Dealing with the sulfur part of cysteine: four enzymatic steps degrade l-cysteine to pyruvate and thiosulfate in Arabidopsis mitochondria. Physiologia plantarum 157 (3):352–366. https://doi.org/10.1111/ppl.12454.
Schwender J, Hebbelmann I, Heinzel N, Hildebrandt T, Rogers A, Naik D, Klapperstück M, Braun H-P, Schreiber F, Denolf P, Borisjuk L, Rolletschek H (2015) Quantitative Multilevel Analysis of Central Metabolism in Developing Oilseeds of Oilseed Rape during in Vitro Culture. Plant physiology 168 (3):828–848. https://doi.org/10.1104/pp.15.00385.
Birke H, Hildebrandt TM, Wirtz M, Hell R (2015) Sulfide detoxification in plant mitochondria. Methods in enzymology 555 (14):271–286. https://doi.org/10.1016/bs.mie.2014.11.027.
Hildebrandt TM, Nunes Nesi A, Araújo WL, Braun H-P (2015) Amino Acid Catabolism in Plants. Molecular plant 8 (11):1563–1579. https://doi.org/10.1016/j.molp.2015.09.005.
Krüßel L, Junemann J, Wirtz M, Birke H, Thornton JD, Browning LW, Poschet G, Hell R, Balk J, Braun H-P, Hildebrandt TM (2014) The mitochondrial sulfur dioxygenase ETHYLMALONIC ENCEPHALOPATHY PROTEIN1 is required for amino acid catabolism during carbohydrate starvation and embryo development in Arabidopsis. Plant physiology 165 (1):92–104. https://doi.org/10.1104/pp.114.239764.
2011-2013
Hildebrandt TM, Di Meo I, Zeviani M, Viscomi C, Braun H-P (2013) Proteome adaptations in Ethe1-deficient mice indicate a role in lipid catabolism and cytoskeleton organization via post-translational protein modifications. Bioscience reports 33 (4):e0052. https://doi.org/10.1042/BSR20130051.
Welchen E, Hildebrandt TM, Lewejohann D, Gonzalez DH, Braun H-P (2012) Lack of cytochrome c in Arabidopsis decreases stability of Complex IV and modifies redox metabolism without affecting Complexes I and III. Biochimica et biophysica acta 1817 (7):990–1001. https://doi.org/10.1016/j.bbabio.2012.04.008.
Jonietz C, Forner J, Hildebrandt T, Binder S (2011) RNA PROCESSING FACTOR3 is crucial for the accumulation of mature ccmC transcripts in mitochondria of Arabidopsis accession Columbia. Plant physiology 157 (3):1430–1439. https://doi.org/10.1104/pp.111.181552.
Hildebrandt TM (2011) Modulation of sulfide oxidation and toxicity in rat mitochondria by dehydroascorbic acid. Biochimica et biophysica acta 1807 (9):1206–1213. https://doi.org/10.1016/j.bbabio.2011.06.003.
Farese S, Stauffer E, Kalicki R, Hildebrandt T, Frey BM, Frey FJ, Uehlinger DE, Pasch A (2011) Sodium thiosulfate pharmacokinetics in hemodialysis patients and healthy volunteers. Clinical journal of the American Society of Nephrology 6 (6):1447–1455. https://doi.org/10.2215/CJN.10241110.
2008-2010
Viscomi C, Burlina AB, Dweikat I, Savoiardo M, Lamperti C, Hildebrandt T, Tiranti V, Zeviani M (2010) Combined treatment with oral metronidazole and N-acetylcysteine is effective in ethylmalonic encephalopathy. Nature medicine 16 (8):869–871. https://doi.org/10.1038/nm.2188.
Hildebrandt T, Grieshaber MK (2009) Die vielen Seiten des Sulfids. Tödlich und doch lebensnotwendig. Biologie in unserer Zeit 39 (5):328–334. https://doi.org/10.1002/biuz.200910403.
Tiranti V, Viscomi C, Hildebrandt T, Di Meo I, Mineri R, Tiveron C, Levitt MD, Prelle A, Fagiolari G, Rimoldi M, Zeviani M (2009) Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy. Nature medicine 15 (2):200–205. https://doi.org/10.1038/nm.1907.
Krueger S, Niehl A, Lopez Martin MC, Steinhauser D, Donath A, Hildebrandt T, Romero LC, Hoefgen R, Gotor C, Hesse H (2009) Analysis of cytosolic and plastidic serine acetyltransferase mutants and subcellular metabolite distributions suggests interplay of the cellular compartments for cysteine biosynthesis in Arabidopsis. Plant, cell & environment 32 (4):349–367. https://doi.org/10.1111/j.1365-3040.2008.01928.x.
Hildebrandt TM, Grieshaber MK (2008) Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. The FEBS journal 275 (13):3352–3361. https://doi.org/10.1111/j.1742-4658.2008.06482.x.
Hildebrandt TM, Grieshaber MK (2008) Redox regulation of mitochondrial sulfide oxidation in the lugworm, Arenicola marina. The Journal of experimental biology 211 (16):2617–2623. https://doi.org/10.1242/jeb.019729.
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